[19] When a difference appears or from the occasion of the dispute, the ultimate determination is manufactured based upon the USP compendial gel clot strategy Until in any other case indicated during the monograph for the solution being tested.[twenty]test for bacterial endotoxins) would be the LAL in vitro testing procedure. The LAL test is only
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Bacterial endotoxins and/or LPS of Gram destructive germs stimulates the host macrophages (which are Skilled antigen presenting cells) to launch inflammatory cytokines as aforementioned; along with the extreme inflammation induced while in the host on account of the discharge of these chemical messengers could trigger numerous organ failures and de
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